Fig. 1
From: Recent advances in materials and flexible electronics for peripheral nerve interfaces
Peripheral nerve interfaces (PNI) consisting of both inserted probes and cuff electrodes damage the target tissue and alter the underlying physiology. Utah slant electrodes (left) inserted into feline sciatic nerves induces inflammation, glial scarring, and rearrangement of the fascicles as shown by histology. Retraction of nerve fibers (green) is shown in the transverse axis while rearrangement of the fibers is shown in the longitudinal axis. This figure is adapted from the following sources and used with permission: Grill et al. (copyright 2000 John Wiley & Sons) (Grill & Mortimer, 2000); Christensen et al. (copyright 2014, Springer) (Christensen et al., 2014)