Fig. 11From: Spinal cord stimulation in chronic pain: evidence and theory for mechanisms of actionECAP-SCS. Newly developed closed-loop SCS system measures evoked compound action potentials (ECAPs) from the spinal cord after each pulse. Greater ECAP amplitude represents more action potentials and is equivalent to increased fiber activation. Variable lead to cord contact occurs with change in position and over time. ECAP-SCS captures and calibrates SCS lead current to target desired ECAP waveform therefore minimizing variability in stimulation, which may improve clinical outcomes. ECAP-SCS is an objective measure of spinal cord activation that may help to predict responders to P-SCSBack to article page