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Fig. 5 | Bioelectronic Medicine

Fig. 5

From: Neuroimaging evaluation of deep brain stimulation in the treatment of representative neurodegenerative and neuropsychiatric disorders

Fig. 5

Correlation of clinical outcome and connectivity to cortical regions of interest. Left panel: Connectivity of stimulation sites to the right middle frontal gyrus (MFG) associated positively with clinical outcome after 12 months of DBS. Right panel: Patient 4 exhibited more robust clinical outcome to DBS with greater connectivity to the caudal part of the MFG region. Patient 6 showed less robust clinical outcome to DBS with relatively sparse connectivity. [Reprinted from Biological Psychiatry 85 (9): 735–743, Baldermann JC, Melzer C, Zapf A, Kohl S, Timmermann L, Tittgemeyer M, Huys D, Visser-Vandewalle V, Kuhn AA, Horn A, Kuhn J. Connectivity profile predictive of effective deep brain stimulation in obsessive-compulsive disorder. Copyright (2019), with permission from Society of Biological Psychiatry]

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