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Fig. 2 | Bioelectronic Medicine

Fig. 2

From: The impact of closed-loop intracortical stimulation on neural activity in brain-injured, anesthetized animals

Fig. 2

Effect of the lesion on firing rate. A) 20-s raster plots of the activity recorded in RFA in a representative Control (CTR) experiment: Pre Lesion - PreL phase (A1), Pre Stim phase - PreS (A2). B) 20-s raster plots of the activity recorded in S1 in a representative Control (CTR) experiment: Pre Lesion - PreL phase (B1), Pre Stim phase - PreS (B2). Each single dot represents a spike; each line of the raster plot reports the activity of a single unit. C) Box plot of the Mean Firing Rate (MFR, spikes/s) of RFA for the entire dataset of CTR experiments. D) Box plot of the Mean Firing Rate (MFR, spikes/s) of S1 for the entire dataset of CTR experiments. For each box plot (C-D), the central black dot indicates the median, the box limits indicate the 25th and 75th percentiles. Whiskers represent the 5th and the 95th percentiles. Dashed line p < 5·10− 2; solid line p < 5·10− 5 Friedman non parametric test. Color code as in Fig. 1C

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