Fig. 6

LvR analysis. Panels on the left refer to RFA area, panels on the right refer to S1 area. In A) LvR distribution shown as histogram with a bin size of 0.05 and determined across all the single units belonging to RFA during pre-lesion phase. In B) LvR distribution shown as histogram with a bin size of 0.05 and determined across all the single units belonging to S1 during pre-lesion phase. In C) Box plot for the CTR group of the LvR calculated between baseline firing rates (PreLesion - PreL) and the subsequent post lesion sessions (PoL1–3 and PreS) in RFA. The central black dot indicates the median, the box limits indicate the 25th and 75th percentiles. Whiskers represent the 5th and the 95th percentiles. D) LvR calculated between baseline firing rates (PreLesion - PreL) and the subsequent post lesion sessions (PoL1–3 and PreS) in S1. In E1) top sketch for CTR group and in the bottom sketch in E2) for ADS, LvR distribution shown as histogram with a bin size of 0.05 and determined across all the single units belonging to RFA during pre and post stimulation phase. E3) Box plot for the CTR group and ADS of the LvR calculated between pre stim firing rates (PreS) and immediately post stim session (PoS) in RFA. The central black dot indicates the median, the box limits indicate the 25th and 75th percentiles. Whiskers represent the 5th and the 95th percentiles. In F1) For CTR and in F2) for ADS, LvR distribution shown as histogram with a bin size of 0.05 and determined across all the single units belonging to S1 during pre and post stimulation phase. F3) For both CTR and ADS, LvR calculated between pre stim firing rates (PreS) and immediately post stim session (PoS) in S1. Friedman test for panels C and D: not significant; *p < 2.5·10− 2, **p < 5·10− 3 Wilcoxon rank-sum test for panels E3 and F3