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Table 2 Comparison of mean differences and 95% confidence intervals of visual analog scale scores, perceived pain reduction and opioid use by between baseline and each individual time point based on stimulator type using paired t-test. For mean differences, the confidence interval is not considered significant if it crosses zero

From: Sex-specific differences in the efficacy of traditional low frequency versus high frequency spinal cord stimulation for chronic pain

 

HF-SCS

p-value

LF-SCS

p-value

Visual Analog Scale Pain Score (mean difference with 95% confidence interval)

 Baseline-Post Implant

0.44(−0.95–0.07)

0.09

− 0.55(− 1.13–0.03)

0.061

 Baseline- 3 Months Post Implant

−2.48(− 3.19-(− 1.77))

< 0.001

− 1.49(− 2.08-(− 0.91))

< 0.001

 Baseline- 6 Months Post Implant

−1.72(− 2.67-(− 0.78))

< 0.001

− 0.86(− 1.45-(− 0.27))

0.005

 Baseline- 12 Months Post Implant

−0.58(− 1.41–0.25)

0.16

−0.42(− 0.99–0.16)

0.15

Perceived Pain Reduction (mean difference with 95% confidence interval)

 Baseline-Post Implant

6.97(5.08–28.86)

0.006

15.18(6.61–23.70)

< 0.001

 Baseline- 3 Months Post Implant

26.75 (14.02–39.48)

< 0.001

14.86(5.12–24.59)

0.004

 Baseline- 6 Months Post Implant

24.0(9.0–39.0)

0.003

8.92(− 1.51–19.35)

0.09

 Baseline- 12 Months Post Implant

31.36(8.88–53.85)

0.01

13.25(−0.15–26.65)

0.052

Morphine Miliequivalents (mean difference with 95% confidence interval)

 Baseline-Post Implant

−1.17(− 10.43–8.09)

0.99

1.84(− 12.77, 16.44)

0.8

 Baseline- 3 Months Post Implant

13.4(− 10.69–37.48)

0.26

15.83(− 17.80, 49.46)

0.35

 Baseline- 6 Months Post Implant

−25.18(− 53.43–3.06)

0.08

3.54(− 23.65, 30.74)

0.79

 Baseline- 12 Months Post Implant

− 15.82(− 37.91–6.26)

0.15

12.73(− 14.62–40.08)

0.36