Fig. 3
From: Evidence of Long-range nerve pathways connecting and coordinating activity in secondary lymph organs
a An ultrasound image of the same popliteal lymph node (LN) before and after electrical stimulation of the sciatic nerve directly above the LN site. The lymph node has been highlighted and the diameter of the lymph node before and after stimulation is shown. b The total weight of excised lymph nodes without (0 mA; sham control) or with electrical stimulation at different stimulation intensities (0.5, 2, 5, 7.5, 10 mA; using stimulation frequency of 20 Hz with 50 msec pulse length). c (left panels) The concentration of white blood cells (WBC), neutrophils (NE), or lymphocytes (LY) taken from the stimulated (direct LN) and other distal lymph nodes (contralateral popliteal and axillary LN) at different times after electrical stimulation of the sciatic nerve above a popliteal lymph node (0, 2, 5, 10, and 30 min following stimulation). (right panels) The concentration of white blood cells (WMC), neutrophils (NE), and lymphocytes (LY) taken from the distal liver, spleen, and lymphatic fluid/lymphatic duct sites at different times after electrical stimulation of the sciatic nerve above a popliteal lymph node (0, 2, 5, 10, and 30 min following stimulation). N = 9. One way ANOVA with multiple comparison analysis * = p ≤ 0.05, ** = p ≤ 0.005,*** = p ≤ 0.0005; Electrical stimulation parameters: 0.5 mA, 20 Hz, pulse length 50 msec