Fig. 4

Temporal raster plots of the continuous breathing rate (Top), and normalized breathing rate (Middle) records as a function of stimulation case (Bottom) for all experimental runs across all animals (N=30). Times were aligned to the start of the ’Stim Only’ epoch to show the transition between the breathing rate during LFAC + vagal stim and vagal stimulation only, which shows a drop in breathing rate when LFAC is removed. Top panel’s breathing rate is the instantaneous rate calculated using the instantaneous interval between inspirations. The middle panel shows the instantaneous breathing rate normalized to the average ’Pre’ epoch breathing rate. Middle panel shows the experimental normalized breathing rate percentage with respect to the averaged breathing rate in ‘pre’ epoch. Bottom panel shows the times when of each stimulation cases were applied