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Fig. 1 | Bioelectronic Medicine

Fig. 1

From: Effects of waveform shape and electrode material on KiloHertz frequency alternating current block of mammalian peripheral nerve

Fig. 1

The simulation environment is setup with a point source electrode 1 mm from a 101 node axon (shown in subfigure A). The three tested waveforms are shown in subfigure B with their 1/12 period discretization. Each waveform was able to achieve block at varying amplitudes, and is shown in voltage plots in subfigure (C). The left column of transmembrane voltage plots shows the voltage of node 0 over time with a test pulse sent as seen in the blue indicator box. The center column shows the voltage over time of the central node (node 50). The right column shows the voltage of node 100 over time and the red indicator box showing where no action potentials are seen, indicating that the test pulse was successfully blocked

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