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Fig. 3 | Bioelectronic Medicine

Fig. 3

From: Electric field responsive nanotransducers for glioblastoma

Fig. 3

TTFields and inorganic NPs (Gold – GNPs; Zinc oxide – ZnO; Silica oxide – SiO2) mediated enhanced EF effects on patient-derived GBM cells. A Schematic representation of TTFields setup consisting of – a base plate containing 8 ceramic dishes is connected to TTFields generator via a flat cable. Cells were seeded on a coverslip placed within a ceramic dish. The base plate is placed inside an incubator where the cells were maintained at 37°C and 5% CO2. B GIN 28 cells and C GCE 28 cells were treated with TTFields at 300 kHz, 1V/cm, and 48 hours at NPs concentration of 5 μg/mL. D GNPs mediated enhanced TTFields effect on GIN 28 cells at 300 kHz, 1V/cm after 48 and 72 hours at a concentration of 25 μg/mL. Error bar represents mean ± S.E.M. from triplicate or quadruplicate repeats and two independent experiments

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