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  1. Neuroimmunomodulation through peripheral nerve activation is an important therapeutic approach to various disorders. Central to this approach is the inflammatory reflex pathway in which the cholinergic anti-in...

    Authors: Shinji Tanaka, Benjamin Hammond, Diane L. Rosin and Mark D. Okusa
    Citation: Bioelectronic Medicine 2019 5:13
    Content type: Review Published on:

  2. Muscle spasticity is a common impediment to motor recovery in patients with chronic stroke. Standard-of-care treatments such as botulinum toxin injections can temporarily relieve muscle stiffness and pain asso...

    Authors: Alexandra Paget-Blanc, Johanna L. Chang, Maira Saul, Regina Lin, Zaghloul Ahmed and Bruce T. Volpe
    Citation: Bioelectronic Medicine 2019 5:11
    Content type: Research article Published on:

  4. Glucose is a crucial energy source. In humans, it is the primary sugar for high energy demanding cells in brain, muscle and peripheral neurons. Deviations of blood glucose levels from normal levels for an exte...

    Authors: Emily Battinelli Masi, Todd Levy, Tea Tsaava, Chad E. Bouton, Kevin J. Tracey, Sangeeta S. Chavan and Theodoros P. Zanos
    Citation: Bioelectronic Medicine 2019 5:9
    Content type: Research article Published on:

  5. Well-established in the field of bioelectronic medicine, Spinal Cord Stimulation (SCS) offers an implantable, non-pharmacologic treatment for patients with intractable chronic pain conditions. Chronic pain is ...

    Authors: Jacob Caylor, Rajiv Reddy, Sopyda Yin, Christina Cui, Mingxiong Huang, Charles Huang, Ramesh Rao, Dewleen G. Baker, Alan Simmons, Dmitri Souza, Samer Narouze, Ricardo Vallejo and Imanuel Lerman
    Citation: Bioelectronic Medicine 2019 5:12
    Content type: Review Published on:

  7. This article [1] has been retracted at the request of the author due to significant overlap with one of his other publications [2] without proper citation. This article is considered redundant. The author agre...

    Authors: Damian Miles Bailey
    Citation: Bioelectronic Medicine 2019 5:7
    Content type: Retraction Note Published on:

    The original article was published in Bioelectronic Medicine 2018 4:13

  8. Glutamatergic neurons represent the largest neuronal class in the brain and are responsible for the bulk of excitatory synaptic transmission and plasticity. Abnormalities in glutamatergic neurons are linked to...

    Authors: Eric H. Chang, Samantha T. Carreiro, Stephen A. Frattini and Patricio T. Huerta
    Citation: Bioelectronic Medicine 2019 5:6
    Content type: Research article Published on:

  10. Rheumatoid arthritis (RA) is a chronic and debilitating inflammatory disease characterized by extensive joint tissue inflammation. Implantable bioelectronic devices targeting the inflammatory reflex reduce TNF...

    Authors: Meghan E. Addorisio, Gavin H. Imperato, Alex F. de Vos, Steve Forti, Richard S. Goldstein, Valentin A. Pavlov, Tom van der Poll, Huan Yang, Betty Diamond, Kevin J. Tracey and Sangeeta S. Chavan
    Citation: Bioelectronic Medicine 2019 5:4
    Content type: Research article Published on:

  11. The loss of motor functions resulting from spinal cord injury can have devastating implications on the quality of one’s life. Functional electrical stimulation has been used to help restore mobility, however, ...

    Authors: Autumn J. Bullard, Samuel R. Nason, Zachary T. Irwin, Chrono S. Nu, Brian Smith, Alex Campean, P. Hunter Peckham, Kevin L. Kilgore, Matthew S. Willsey, Parag G. Patil and Cynthia A. Chestek
    Citation: Bioelectronic Medicine 2019 5:3
    Content type: Research article Published on:

  12. The Cleveland Neural Engineering Workshop (NEW) was established as a biennial meeting in 2011, with subsequent meetings taking place in 2013, 2015, and most recently, June 2017. This fourth biennial NEW was ho...

    Authors: Dustin J. Tyler, Christopher J. Czura, Jennifer French, Kip Ludwig, Kevin Otto, Forrest Pape and Cristin Welle
    Citation: Bioelectronic Medicine 2019 5:2
    Content type: Meeting report Published on:

  14. The Cleveland Neural Engineering Workshop (NEW) is a biennial meeting started in 2011 as an “unconference” to bring together leaders in the neural engineering and related fields. Since the first iteration of t...

    Authors: Kim Anderson, Abidemi Ajiboye, Timothy Denison, Jennifer French, Kenneth Gustafson, Kevin Kilgore, Naomi Kleitman, Audrey Kusiak, Brian Litt, Megan Moynahan, Eric Perreault, Douglas Weber, Justin Williams and Dustin Tyler
    Citation: Bioelectronic Medicine 2018 4:15
    Content type: Meeting report Published on:

  16. Rising atmospheric oxygen (O2) levels provided a selective pressure for the evolution of O2-dependent micro-organisms that began with the autotrophic eukaryotes. Since these primordial times, the respiring mammal...

    Authors: Damian Miles Bailey
    Citation: Bioelectronic Medicine 2018 4:13
    Content type: Review Published on:

    The Retraction Note to this article has been published in Bioelectronic Medicine 2019 5:7

  19. Understanding the long-term behavior of intracortically-recorded signals is essential for improving the performance of Brain Computer Interfaces. However, few studies have systematically investigated chronic n...

    Authors: Mingming Zhang, Michael A. Schwemmer, Jordyn E. Ting, Connor E. Majstorovic, David A. Friedenberg, Marcia A. Bockbrader, W. Jerry Mysiw, Ali R. Rezai, Nicholas V. Annetta, Chad E. Bouton, Herbert S. Bresler and Gaurav Sharma
    Citation: Bioelectronic Medicine 2018 4:11
    Content type: Research article Published on:

  22. The role of the kidney in glucose homeostasis has gained global interest. Kidneys are innervated by renal nerves, and renal denervation animal models have shown improved glucose regulation. We hypothesized tha...

    Authors: Ahmad A. Jiman, Kavaljit H. Chhabra, Alfor G. Lewis, Paul S. Cederna, Randy J. Seeley, Malcolm J. Low and Tim M. Bruns
    Citation: Bioelectronic Medicine 2018 4:7
    Content type: Research article Published on:

  24. Vagus nerve stimulation (VNS) is a promising therapy for many neurologic and psychiatric conditions. However, determining stimulus parameters for individual patients is a major challenge. The traditional metho...

    Authors: Kurt Y. Qing, Kelsey M. Wasilczuk, Matthew P. Ward, Evan H. Phillips, Pavlos P. Vlachos, Craig J. Goergen and Pedro P. Irazoqui
    Citation: Bioelectronic Medicine 2018 4:5
    Content type: Research article Published on:

  26. The vagus nerve plays an important role in the regulation of organ function, including reflex pathways that regulate immunity and inflammation. Recent studies using genetically modified mice have improved our ...

    Authors: Harold A. Silverman, Andrew Stiegler, Téa Tsaava, Justin Newman, Benjamin E. Steinberg, Emily Battinelli Masi, Sergio Robbiati, Chad Bouton, Patricio T. Huerta, Sangeeta S. Chavan and Kevin J. Tracey
    Citation: Bioelectronic Medicine 2018 4:3
    Content type: Research article Published on:

  28. Cellular homeostasis is in part controlled by biological generated electrical activity. By interfacing biology with electronic devices this electrical activity can be modulated to actuate cellular behaviour. T...

    Authors: Paola Sanjuan-Alberte, Morgan R. Alexander, Richard J. M. Hague and Frankie J. Rawson
    Citation: Bioelectronic Medicine 2018 4:1
    Content type: Review Published on:

  29. The axons of the sensory, or afferent, vagus nerve transmit action potentials to the central nervous system in response to changes in the body’s metabolic and physiological status. Recent advances in identifyi...

    Authors: Benjamin E. Steinberg, Harold A. Silverman, Sergio Robbiati, Manoj K. Gunasekaran, Téa Tsaava, Emily Battinelli, Andrew Stiegler, Chad E. Bouton, Sangeeta S. Chavan, Kevin J. Tracey and Patricio T. Huerta
    Citation: Bioelectronic Medicine 2016 3:3010007
    Content type: Research Article Published on:

  30. When pathogens and toxins breech the epithelial barrier, antigens are transported by the lymphatic system to lymph nodes. In previously immunized animals, antigens become trapped in the draining lymph nodes, b...

    Authors: William M. Hanes, Peder S. Olofsson, Sébastien Talbot, Tea Tsaava, Mahendar Ochani, Gavin H. Imperato, Yaakov A. Levine, Jesse Roth, Maud A. Pascal, Simmie L. Foster, Ping Wang, Clifford Woolf, Sangeeta S. Chavan and Kevin J. Tracey
    Citation: Bioelectronic Medicine 2016 3:3010018
    Content type: Research Article Published on:

  31. Vagus nerve stimulation (VNS) has been used since 1997 for treatment of drug-resistant epilepsy. More recently, an off-label use of VNS has been explored in animal models and clinical trials for treatment of a...

    Authors: Harwood Kwan, Luca Garzoni, Hai Lun Liu, Mingju Cao, Andre Desrochers, Gilles Fecteau, Patrick Burns and Martin G. Frasch
    Citation: Bioelectronic Medicine 2016 3:3010001
    Content type: Review Article Published on:

  32. Introducing neural sensing and decoding to open-loop neurostimulation technologies has the potential to significantly improve the diagnosis and treatment of a wide variety of diseases treated through bioelectr...

    Authors: Gaurav Sharma, Nicholas Annetta, David Friedenberg, Tony Blanco, Daphne Vasconcelos, Ammar Shaikhouni, Ali R. Rezai and Chad Bouton
    Citation: Bioelectronic Medicine 2015 2:2010063
    Content type: Research Article Published on:

  33. Hypertension (HTN) affects over 1 billion people in the world, and while most are treated effectively with pharmacological regimens, 10–30% of them do not show a beneficial response. Electrical stimulation of ...

    Authors: Young-tae Kim, Aswini Kanneganti, Caleb Nothnagle, Ryan Landrith, Masaki Mizuno, Muthu B. J. Wijesundara, Scott Smith and Mario I. Romero-Ortega
    Citation: Bioelectronic Medicine 2015 2:2010055
    Content type: Research Article Published on:

  36. Christopher J. Czura, PhD, is Vice President of the Feinstein Institute for Medical Research, Executive Publisher of the Feinstein Institute Press’s international, peer-reviewed journals, Molecular Medicine and B...

    Authors: Christopher J. Czura
    Citation: Bioelectronic Medicine 2015 2:2010049
    Content type: Commentary Published on:

  37. When a peripheral nerve is injured after either trauma or a neurodegenerative disease, motor function and sensory perception are impaired. Repair strategies aim both at reconstructing the damaged nerve and in ...

    Authors: Miyuki Sakuma, Ivan R. Minev, Sandra Gribi, Bhagat Singh, Clifford J. Woolf and Stéphanie P. Lacour
    Citation: Bioelectronic Medicine 2015 2:2010043
    Content type: Invited Review Article Published on:

  38. The inflammatory reflex is a neural circuit defined by action potentials transmitted in the vagus nerve that regulate cytokine production in the spleen. Detailed mechanistic studies implicate the vagus nerve, ...

    Authors: Peder S. Olofsson, Yaakov A. Levine, April Caravaca, Sangeeta S. Chavan, Valentin A. Pavlov, Michael Faltys and Kevin J. Tracey
    Citation: Bioelectronic Medicine 2015 2:2010037
    Content type: Research Article Published on:

  39. Along the gut, there are rhythmic myoelectrical activities called slow waves that regulate gastrointestinal motility. Impairment in gastrointestinal slow waves and motility causes various disorders such as gas...

    Authors: Jieyun Yin and Jiande D. Z. Chen
    Citation: Bioelectronic Medicine 2015 2:2010013
    Content type: Invited Review Article Published on:

  41. Neural decoding is a field involving the use of signal processing and machine learning methods to decode brain activity for various applications including assistive technology for people living with paralysis ...

    Authors: Chad Bouton
    Citation: Bioelectronic Medicine 2015 2:2010020
    Content type: Invited Review Article Published on:

  44. Bioelectronic medicine aims to understand and harness the beneficial effects of the nervous system and neural circuits to diagnose, treat and prevent disease. For example, targeted electrical stimulation devic...

    Authors: Jason R. Fritz and Jared M. Huston
    Citation: Bioelectronic Medicine 2014 1:1010025
    Content type: Proceedings Published on:

  48. Traumatic brain injury is a serious public health problem in the United States, accounting for nearly 1.7 million injuries and 52,000 deaths annually. The initial brain injury is made worse by secondary events...

    Authors: Chunyan Li and Raj K. Narayan
    Citation: Bioelectronic Medicine 2014 1:1010004
    Content type: Proceedings Published on:
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Bioelectronic Medicine

ISSN: 2332-8886